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sdpB [2019-02-04 15:52:05]
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sdpB [2019-02-04 15:52:05]

membrane protein, required for SdpC toxin maturation
locus
BSU33760
pI
9.52
mw
37.30 kDa
protein length
323 aa Sequence Blast
gene length
972 bp Sequence Blast
function
maturation of the SdpC toxin
product
unknown
essential
no
synonyms
yvaX
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.17|Toxins, antitoxins and immunity against toxins]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    3,464,762 3,465,733

    The protein

    [SW|Localization]

  • cell membrane [Pubmed|18763711]

    • Expression and Regulation

    Operons

    genes
    [gene|219092C574A13B81CD312AEB55BAE48A3C541FB7|sdpA]-[gene|073D63E17C8248BE39F331FDE9902E21A34056D5|sdpB]-[gene|820635420B3980B620F3E3D7ACF7EDE9DC6275AD|sdpC]
    description
    [Pubmed|12817086]

    regulatory mechanism

  • [protein|2C54FE2ADC82FF414D732018C90649D477A925AD|Spo0A]: activation, [PubMed|14651647,15687200], in [regulon|2C54FE2ADC82FF414D732018C90649D477A925AD|Spo0A regulon]
  • [protein|1508770D5BCA5739D13E3ABD11CC5C103C07FF25|Rok]: repression, [Pubmed|15743949], in [regulon|1508770D5BCA5739D13E3ABD11CC5C103C07FF25|Rok regulon]
  • [protein|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB]: repression, [PubMed|15687200,17720793], in [regulon|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB regulon]

    • regulation

  • expressed under conditions that trigger sporulation ([SW|Spo0A]) [http://www.ncbi.nlm.nih.gov/sites/entrez/14651647,15687200 PubMed]

    • additional information

  • the amount of the mRNA is substantially decreased upon depletion of [gene|872CCB5A49C9000BD95E4B0472556D5F60F7D7A4|RNase Y] [PubMed|21815947]
    • view in new tab

    Biological materials

    Mutant

  • MGNA-A449 (yvaX::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/449 NBRP B. subtilis, Japan]
  • BKE33760 ([gene|073D63E17C8248BE39F331FDE9902E21A34056D5|sdpB]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE33760 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CTTCATACTATTTTTATTTT, downstream forward: _UP4_TAACATTTAGATAATGGAGA
  • BKK33760 ([gene|073D63E17C8248BE39F331FDE9902E21A34056D5|sdpB]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK33760 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CTTCATACTATTTTTATTTT, downstream forward: _UP4_TAACATTTAGATAATGGAGA

    • References

    Reviews

  • 20955377

    • Original Publications

  • 12817086,14651647,15687200,15743949,15687200,17720793,18763711,23687264,21815947,23033921